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Experts Corner

Perinatal Pathology

Pregnant After Complete Trisomy 22
By Carolyn M. Salafia, MD

Carolyn Salafia, MDQ. I miscarried last August at almost 12 weeks. After genetic testing, I was told it was a complete trisomy 22. I am six weeks pregnant now. I turned 40 on the day I got pregnant. I have a beautiful healthy 3 year old son. What are the chances of having another healthy baby?

A. Pretty darn good! Trisomy 22 is a common cause of pretty standard random wrong chromosome accident, and something that would really be reasonably expected to be secondary to age alone. Given the egg with a good chromosome number, you should be in great shape


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